Tobacco (Nicotiana tabacum) Ca2+-dependent protein kinase 1 (NtCDPK1) is involved in feedback regulation of the plant hormone gibberellin through the phosphorylation of the transcription factor, REPRESSION OF SHOOT GROWTH (RSG).Previously, Ser-6 and Thr-21 were identified as autophosphorylation sites in NtCDPK1.Autophosphorylation of Ser-6 and Thr-
Antimicrobial Activity of Selected Banana Cultivars Against Important Human Pathogens, Including Candida Biofilm
Ten banana (Musa spp.) cultivars were studied for their antimicrobial properties.Three plant parts (corm, pseudostem and leaves) were collected separately and extracted with different solvents, viz., hexane, acetone, ethanol and water.The 50% inhibitory concentration (IC50) was evaluated using a broth microdilution assay.Eight human bacterial and o
Efficacy of anti-PD-1 and ipilimumab alone or in combination in acral melanoma
Background Acral melanoma is a rare melanoma subtype with poor prognosis.Importantly, these patients were not identified as a specific subgroup in the landmark melanoma trials involving ipilimumab and the anti-programmed cell death protein-1 (PD-1) agents nivolumab and pembrolizumab.There is therefore an absence of prospective clinical trial eviden
Broadband On-Chip Mode-Division Multiplexer Based on Adiabatic Couplers and Symmetric Y-Junction
The mode-division multiplexer/demultiplexer (MMUX/DeMMUX) is the crucial component for the implementation of mode-division multiplexing (MDM) transmission.We propose an on-chip two-mode MMUX/DeMMUX based on adiabatic couplers.Thanks to the principle of mode evolution, the proposed MMUX possesses advantages of broadband Rough Rider operation and hig
Do Rumen Bacteroidetes Utilize an Alternative Mechanism for Cellulose Degradation?
ABSTRACT Uncultured and therefore uncharacterized Bacteroidetes lineages are ubiquitous in many natural ecosystems which specialize in lignocellulose degradation.However, their metabolic contribution remains mysterious, as well-studied cultured Bacteroidetes have been shown to degrade only soluble kids hats polysaccharides within the human distal g